Shuffle the Test Set and Protein AI's Best Scores Collapse
New benchmarking work reports that protein language model scores fall sharply once homologous sequences are kept out of the test set. The problem is well documented.
Editor's picks
See allThe Next Pandemic Won't Have the Symptoms You're Watching For
Outbreak detection still runs on fixed symptom checklists. A new Nature comment argues for symptom preparedness, and gives AI one narrow job.
AI Models Cells Across a Billion Years. Can They Beat Plain PCA?
Just Describe the Protein You Want. This AI Builds It, and It Works
Measles Elimination Now Hinges on 450 Letters of Viral Code
AI Can Call Drug Resistance in Hours. Should Labs Trust It Yet?
AI
See allVirology
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See allNo Federal AI Law? How US States Are Quietly Writing the Rules for Health AI
The US still has no federal AI law. We map how state AI laws now govern health AI, from chatbot crisis rules to human review of insurance denials, and what federal preemption could change.
AI-Designed Longevity Drugs Are in Human Trials. Do Any of Them Work?
AI drug discovery has put the first ageing-focused drugs into human trials. We weigh the evidence on rentosertib, BGE-102, RLS-1496 and the ageing clocks used to judge them.
AI Is Reading Disease One Cell at a Time. Is the Hype Ahead of the Data?
Single cell sequencing now profiles hundreds of millions of cells, and AI foundation models such as scGPT and Geneformer promise to map disease cell by cell. Here is what the evidence supports.
Can AI Read DNA Without Being Taught the Genetic Code?
Codon-free models learn protein biology straight from raw DNA, with no translation table supplied. Here is what the evidence actually shows, and where these models still fall short.
If Your DNA Trains an AI That Finds a Blockbuster Drug, Who Gets Paid?
Who owns genetic data once it trains an AI model? We look at the law, the 23andMe bankruptcy, UK Biobank, the Cali Fund and benefit sharing to find out who profits.
AI Is Rewiring Microbes to Brew Our Medicines. Is It Working?
Synthetic biology is handing the design of medicine-making microbes to machine learning. We look at what AI-guided strain engineering has actually delivered, where it still stalls, and what the evidence supports.
AI in Healthcare
See allAI Can Call Drug Resistance in Hours. Should Labs Trust It Yet?
AI diagnostics can now predict antibiotic and antiviral resistance from a pathogen genome with striking accuracy. We examine the 2026 evidence, and why Europe's own susceptibility testing committee says it is not ready for the clinic.