How a New AI Out-Predicts AlphaFold 3 on Protein Metal Ions
BiteNetI, a new deep-learning model, out-predicts AlphaFold 3 at finding protein metal-ion binding sites, a blind spot for today's protein language models.
Protein Language Models Just Learned to Think in 3D
A new bioRxiv preprint, Prot-LAMBDA, teaches protein language models explicit 3D geometry and reportedly matches a model five times its size. Why efficiency, not scale, is the real story.
How a Protein Language Model Is Reading the Gut's Enzyme Dark Matter
A new Science Advances study uses a protein language model to annotate enzyme 'dark matter' in the gut microbiome, mapping metabolism in health and inflammatory bowel disease.